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It is at least as accurate and more versatile as commercially available programs such as CLogP.
It has been tested by researchers at the Pharmaceutical Products Division of Abbott Laboratories and found as being one of the better programs for logP prediction.
XLogP is based on a group contribution method, but with some corrections (e.g. for the nature of the first neighbour of a group). The group contribution was developed using a training set of 1831 organic compounds.
Accuracy of XLogP calculations
The octanol/water partition coefficient is the most popular measure of the hydrophobicity / hydrophilicity of organic compounds. Usually it is the required quantity for legal issues e.g. concerning toxicity (the more hydrophobic a compound, the more easily is its uptake in (human) fat).
Also it is a good measure of the solubility in water and organic compounds, although also other factors (e.g. the stability of the crystalline material) play a role.